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Human IFN-gamma R1 / IFNGR1 Protein, His Tag

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IF1-H5223-200ug
¥3045.00
IF1-H5223-1mg (500ug X 2)
¥12600.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    IFNGR1,CD119,CDw119,IFNGR,IFN-gamma-R1

  • 表达区间及表达系统(Source)

    Human IFN-gamma R1, His Tag (IF1-H5223) is expressed from human 293 cells (HEK293). It contains AA Glu 18 - Gly 245 (Accession # AAH05333).

    Predicted N-terminus: Glu 18

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    IFN-gamma R1 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 26.6 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    IFN-gamma R1 SDS-PAGE

    Human IFN-gamma R1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • 活性(Bioactivity)-ELISA

     IFN-gamma R1 ELISA

    Immobilized Human IFN-gamma, premium grade (Cat. No. IFG-H4211) at 5 μg/mL (100 μL/well) can bind Human IFN-gamma R1, His Tag (Cat. No. IF1-H5223) with a linear range of 0.01-0.313 μg/mL (Routinely tested).

    Protocol

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背景介绍

Interferon gamma receptor 1 (IFNGR1) is also known as CD antigen CD119, which belongs to the type II cytokine receptor family. IFNGR1 contains two fibronectin type-III domains and two Ig-like C2-type (immunoglobulin-like) domains. IFNGR1 / CD119 is receptor for interferon gamma. Two receptors bind one interferon gamma (IFNG) dimer.

前沿进展

 
药物研发进展
  • 英文全称:

    Interferon gamma receptor

  • 中文全称:

    干扰素γ受体复合体

  • 种类:

  • 上市药物数量:

    11 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    批准上市

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